GeoMx Protein and RNA assays allow you to profile up to 96 targets with nCounter readout or 10’s-100’s of protein targets or >1,800 RNA targets with NGS readout from a single FFPE or fresh frozen slide with Digital Spatial Profiling. GeoMx Assays are pre-validated and modular to provide flexibility and support a range of research needs. For protein, select one 20-plex core and add 10-plex modules to analyze ______expression______ of your proteins of interest. Additionally, antibodies can be customized for use with GeoMx® DSP through the Protein Barcoding Service and from Abcam. For RNA, select a core panel with the option to add custom user defined content.

Available content covers immunology, immuno-oncology, neurodegeneration, and neuroinflammation with a rapidly growing pipeline.

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See below for detailed assay information.

GeoMx® Protein Assays for nCounter

Designed to profile up to 96 protein targets simultaneously with spatial resolution using the nCounter® platform.

Immuno-Oncology and Immunology

The Immune Cell Profiling Core contains 18 targets for broad cell profiling of human samples (17 targets for mouse) and includes necessary controls for all GeoMx DSP experiments. Up to six 10-plex modules plus 10 custom targets can be added to select the content most relevant to your human and mouse research.

Neuroscience

The Neural Cell Profiling Core contains 20 targets designed for broad cell profiling of human samples (19 targets for mouse) and includes necessary controls for all GeoMx DSP experiments. Up to six 10-plex modules plus 10 custom targets can be added to select the content most relevant to your human and mouse research.

GeoMx® RNA Assays for nCounter

The 84-plex Immune Pathways panel profiles RNA targets simultaneously, with the option to add up to 10 custom RNA probes, with spatial resolution using the nCounter® platform.