CellScape
(The Next Generation of ChipCytometry¢â Instrumentation)
The Next-Generation ChipCytometry Instrument
CellScape¢â is an end-to-end solution for highly multiplexed spatial omics. Combining an advanced, purpose-built imaging system with easy-to-use fluidics for walk-away automation, the CellScape system will accelerate your exploration into the rapidly evolving field of spatial biology.
Feature
- 1
Highly Multiplexed
Measure virtually unlimited protein biomarkers on a single sample
- 2
Throughput and automation
Analyze four samples at a time with walk-away automation
- 3
Precision Imaging
Combine High Resolution and innovative High Dynamic Range for true single-cell quantification
- 4
Versatile
Open-source reagents, no proprietary conjugations
Ease to Use Workflow
Simple Chemistry and High Sensitivity
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-Direct fluorescently labelled antibody:
No need barcoding, No custom conjugation
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-Filtered Photobleaching method:
No need to strip the antibody, Preserves Sample quality
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-Faster antibody marker validation
CellScape¡¯s filterd photobleaching preserves signal and epitope stability
High Resolution
Broad Scan Area(44mm X 16mm):
whole slide imaging, Multiple Samples
Specification
Dimensions | CellScape Instrument: 57 cm x 38 cm x 32 cm PlexFlo Fluidics Unit: 37 cm x 30 cm x 20 cm |
|
Weight | 60 kg | |
Additional Components | Light source, eBox, degasser, computer and monitor, barcode scanner | |
Automation | Walk-away staining, image acquisition, and photo-inactivation | |
Light Source | 120 W Mercury arc lamp | |
Imaging Modes | Transmitted and fluorescence light | |
Sample Compatibility | FFPE tissues, FF tissues, Cell suspensions | |
Fluorescence Channels | Spectrally distinct filter sets for 5 color imaging | |
File Formats | OME-TIFF files | |
Software | CellScape¢â Navigator: Single application that integrates experiment planning, instrument control, and data export. |
CellScape Standard Mode | CellScape FalconFAST Mode | |
---|---|---|
Objective | Plan Apo 20X | 0.80 NA | Plan Fluor 10X | 0.30 NA |
FOV Size | 0.8 mm2 | 3.3 mm2 |
Resolution* | 278 nm | 742 nm |
Digital Sampling** | 182 nm/pixel | 365 nm/pixel |
* Resolution is calculated with the following equation: r = 0.61¥ë/NA using the shortest excitation wavelength (¥ë = 365 nm). The resolution in other channels will be higher.
** Digital sampling is independent of resolution and is calculated by dividing the pixel size of the camera by magnification.